Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903813 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27759642 | 0.98 | TSHR (0.59) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL28644407 | 0.93 | TSHR (0.53) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL21783982 | 0.91 | TSHR (0.52) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL27517912 | 0.88 | TSHR (0.48) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL219555 | 0.86 | — | — | |
| SCHEMBL28538098 | 0.85 | TSHR (0.46) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL7951034 | 0.82 | TSHR (0.44) | TSHRALDH1A1RECQLGAAEPHX2 | |
| SCHEMBL8958415 | 0.81 | TSHR (0.41) | TSHRALDH1A1RECQLGAASMN1; SMN2 | |
| SCHEMBL11382562 | 0.81 | TSHR (0.65) | TSHRALDH1A1RECQLGAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177437-B1 | VIRICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER | 2001-01-23 | — | — | US | disclosed |