SCHEMBL8958415

SCHEMBL8958415

NC(=O)NCCCOCCCNC(N)=O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CA2 P00918 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.38
RECQL P46063 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
ACHE P22303 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958400 0.98 CA2 (0.42) TSHRCA2TDP1MAPTHSD17B10
SCHEMBL12461744 0.98 CA2 (0.42) TSHRCA2TDP1MAPTHSD17B10
Ethylene Glycol SCHEMBL8958389 0.93 GAA (0.40) TSHRCA2TDP1MAPTHSD17B10
SCHEMBL6289744 0.91 GAA (0.43) TSHRCA2TDP1MAPTHSD17B10
SCHEMBL6284265 0.89 TSHR (0.39) TSHRCA2MAPTHSD17B10RECQL
SCHEMBL15019063 0.89 EPHX2 (0.43) TSHRMAPTHSD17B10RECQLALDH1A1
SCHEMBL22970104 0.89 CA2 (0.39) TSHRCA2TDP1MAPTHSD17B10
SCHEMBL27517912 0.88 TSHR (0.48) TSHRCA2MAPTHSD17B10RECQL
SCHEMBL20724724 0.87 TSHR (0.56) TSHRHSD17B10ALDH1A1HTTNPC1
SCHEMBL6290119 0.86 SAT1 (0.42) TSHRMAPTHSD17B10RECQLHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641402-B1 CONTINUOUS DYEING OF CELLULOSE-CONTAINING TEXTILES BASF AG (DE) 1996-09-11 EP disclosed
US-5484457-A Continuous production of surface dyeings on cellulose fiber textile materials BASF AKTIENGESELLSCHAFT (DE) 1996-01-16 US disclosed
EP-0358087-B1 Quaternized condensation products BASF AG (DE) 1995-07-12 EP disclosed
WO-1993023605-A1 CONTINUOUS DYEING OF CELLULOSE-CONTAINING TEXTILES BASF AKTIENGESELLSCHAFT (DE) 1993-11-25 WO disclosed
US-5224963-A Improving perspiration fastness BASF AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
US-5015754-A Cationic polyethers for fixing reative and direct dyes used for dyeing and printing cellulose textiles; washfastness BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
EP-0358087-A2 Quaternized condensation products BASF Aktiengesellschaft (DE) 1990-03-14 EP disclosed