Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684446 | 0.88 | EGLN1 (0.70) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7683265 | 0.88 | EGLN1 (0.72) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7956952 | 0.86 | MEN1 (0.79) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8309972 | 0.86 | EGLN1 (0.71) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4064897 | 0.85 | HIF1A (0.52) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8310038 | 0.83 | EGLN1 (1.00) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7692316 | 0.82 | EGLN1 (1.00) | EGLN1MEN1KMT2AALDH1A1 | |
| SCHEMBL7690012 | 0.81 | EGLN1 (0.67) | EGLN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7687034 | 0.81 | EGLN1 (0.66) | EGLN1MEN1KMT2AP2RX7ALDH1A1 | |
| SCHEMBL7690447 | 0.80 | EGLN1 (0.84) | EGLN1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |