Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951114 | 0.86 | EGLN1 (0.71) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL8309972 | 0.86 | EGLN1 (0.71) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL8310038 | 0.83 | EGLN1 (1.00) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL7957180 | 0.82 | EGLN1 (0.80) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL7690012 | 0.81 | EGLN1 (0.67) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL7690447 | 0.80 | EGLN1 (0.84) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL7691139 | 0.80 | EGLN1 (0.67) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL5228962 | 0.79 | PTGS2 (0.65) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL7683265 | 0.79 | EGLN1 (0.72) | MEN1NPC1RAB9AKMT2AEGLN1 | |
| SCHEMBL2292957 | 0.79 | EGLN1 (0.86) | NPC1RAB9AEGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |