SCHEMBL7951352

SCHEMBL7951352

[SiH3][Hf](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8560772 0.86 HTR6 (0.30) HTR2AHTR6
SCHEMBL215792 0.80 HTR2A (0.35) HTR2AHTR6
SCHEMBL3383168 0.80 HTR2A (0.35) HTR2AHTR6SIGMAR1
Hydrochloric Acid SCHEMBL6339337 0.78 HTR2A (0.34) HTR2AHTR6SIGMAR1
SCHEMBL3383074 0.77 HTR6 (0.33) HTR2AHTR6SIGMAR1
SCHEMBL7935464 0.77 HTR6 (0.31) HTR2AHTR6
SCHEMBL4470704 0.76 HTR6 (0.36) HTR2AHTR6SIGMAR1
SCHEMBL15283338 0.76 HTR2A (0.36) HTR2AHTR6SIGMAR1
SCHEMBL15334065 0.76 HTR6 (0.33) HTR2AHTR6
Hydrochloric Acid SCHEMBL7107339 0.76 KDM4E (0.33) HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001098381-A2 POLYMERIZATION PROCESS USING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
EP-1037931-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 2000-09-27 EP disclosed
WO-1999029738-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 1999-06-17 WO disclosed