Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.74 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.74 |
| ▸ | NQO2 | P16083 | 12/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956027 | 0.93 | MTNR1A (0.85) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7943640 | 0.86 | MTNR1A (0.86) | MTNR1AMTNR1BNQO2TRPV1ABCB1 | |
| SCHEMBL7943746 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7951212 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7950457 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8887034 | 0.84 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2TRPV1ABCB1 | |
| SCHEMBL8886905 | 0.83 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2TRPV1ABCB1 | |
| SCHEMBL8887184 | 0.82 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7953882 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8431901 | 0.79 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |