SCHEMBL7951397

SCHEMBL7951397

CC(=O)OCc1cnc(-c2ccccc2)n(CC(=O)NC(Cc2ccccc2)C(=O)C(=O)CCCOc2ccccn2)c1=O

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 17/20 0.45
CTRC Q99895 10/20 0.45
ELANE P08246 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7961182 0.93 CMA1 (0.46) CMA1CTRC
SCHEMBL6708761 0.90 CMA1 (0.46) CMA1CTRC
SCHEMBL7950471 0.90 CMA1 (0.45) CMA1CTRC
SCHEMBL7962870 0.87 CMA1 (0.44) CMA1CTRC
SCHEMBL7959687 0.87 ELANE (0.41) CMA1CTRCELANE
SCHEMBL7960975 0.87 CMA1 (0.43) CMA1CTRC
SCHEMBL6710145 0.87 ELANE (0.47) CMA1CTRCELANE
SCHEMBL6706856 0.86 CMA1 (0.58) CMA1CTRC
SCHEMBL7951052 0.86 CTRC (0.47) CMA1CTRC
Hydrochloric Acid SCHEMBL7566410 0.86 CMA1 (0.57) CMA1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300337-B1 Acetamide derivative and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2001-10-09 US claimed
US-6300337-B1 Acetamide derivative and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2001-10-09 US disclosed
EP-1055683-A1 NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2000-11-29 EP disclosed