Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955632 | 0.88 | HPGD (0.45) | IDH1ALDH1A1MAPTBRD4CREBBP | |
| SCHEMBL7955418 | 0.86 | TSHR (0.47) | IDH1ALDH1A1MAPTBRD4CREBBP | |
| SCHEMBL7829876 | 0.85 | IDH1 (0.48) | IDH1ALDH1A1POLBHTTKMT2A | |
| SCHEMBL30960380 | 0.75 | MAPT (0.53) | ALDH1A1KMT2AMAPTBRD4CREBBP | |
| SCHEMBL219216 | 0.75 | MAPT (0.53) | ALDH1A1KMT2AMAPTBRD4CREBBP | |
| SCHEMBL17432610 | 0.75 | HTT (0.45) | ALDH1A1POLBHTTMAPTTP53 | |
| SCHEMBL29088284 | 0.74 | BRD4 (0.46) | IDH1ALDH1A1MAPTBRD4CREBBP | |
| SCHEMBL28440060 | 0.73 | MAPT (0.46) | ALDH1A1HTTKMT2AMAPTBRD4 | |
| SCHEMBL30462621 | 0.73 | MAPT (0.46) | ALDH1A1HTTKMT2AMAPTBRD4 | |
| Hydrochloric Acid SCHEMBL27483776 | 0.71 | IDH1 (0.34) | IDH1KMT2ABRD4CREBBPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |