Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.40 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955632 | 0.99 | HPGD (0.45) | TSHRHPGDALDH1A1IDH1DPP4 | |
| SCHEMBL7951635 | 0.86 | IDH1 (0.52) | TSHRALDH1A1IDH1BRD4CREBBP | |
| SCHEMBL7829876 | 0.84 | IDH1 (0.48) | TSHRALDH1A1IDH1MAPT | |
| SCHEMBL219216 | 0.77 | MAPT (0.53) | HPGDALDH1A1BRD4CREBBPKDM4E | |
| SCHEMBL30960380 | 0.77 | MAPT (0.53) | HPGDALDH1A1BRD4CREBBPKDM4E | |
| SCHEMBL29088284 | 0.76 | BRD4 (0.46) | ALDH1A1IDH1BRD4CREBBPGAA | |
| SCHEMBL4999846 | 0.75 | GAA (0.59) | TSHRHPGDDPP4FAPPREP | |
| SCHEMBL28440060 | 0.75 | MAPT (0.46) | HPGDALDH1A1BRD4CREBBPKDM4E | |
| SCHEMBL30462621 | 0.75 | MAPT (0.46) | HPGDALDH1A1BRD4CREBBPKDM4E | |
| SCHEMBL14073993 | 0.74 | GAA (0.61) | TSHRHPGDDPP4FAPPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |