Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962700 | 0.87 | ELANE (0.49) | ELANECTSGTSHR | |
| SCHEMBL7370365 | 0.84 | ELANE (0.60) | ELANECTSG | |
| SCHEMBL7952685 | 0.83 | ELANE (0.62) | ELANECTSGTSHR | |
| SCHEMBL7963862 | 0.82 | ELANE (0.58) | ELANECTSGTSHR | |
| SCHEMBL6744559 | 0.82 | ELANE (0.58) | ELANECTSG | |
| SCHEMBL7860575 | 0.82 | ELANE (0.41) | ELANE | |
| SCHEMBL7964090 | 0.82 | ELANE (0.51) | ELANECTSG | |
| SCHEMBL7960590 | 0.80 | ELANE (0.40) | ELANECTSG | |
| SCHEMBL7951785 | 0.80 | ELANE (0.69) | ELANECTSG | |
| SCHEMBL7960490 | 0.79 | ELANE (0.51) | ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265381-B1 | MORPHOLINOUREA AND RELATED DERIVATIVES OF PENTAFLUOROETHYL PEPTIDES | MERRELL PHARMACEUTICALS, INC. | 2001-07-24 | — | — | US | disclosed |