Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PKLR | P30613 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699675 | 0.93 | KMT2A (0.56) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL7955499 | 0.93 | KMT2A (0.56) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL7944872 | 0.88 | KMT2A (0.51) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL1677064 | 0.87 | TP53 (0.60) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL1677163 | 0.86 | KMT2A (0.58) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL18726870 | 0.85 | ALDH1A1 (0.63) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL12727839 | 0.83 | HTT (0.62) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL1676973 | 0.83 | CNR1 (0.63) | TP53HTTGAAHPGDCNR1 | |
| SCHEMBL1677094 | 0.82 | TP53 (0.55) | KMT2AMEN1TP53HTTGAA | |
| SCHEMBL1677096 | 0.82 | TP53 (0.55) | KMT2AMEN1TP53HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-B1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO (JP) | 2013-02-13 | — | — | EP | disclosed |
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |