Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945554 | 0.92 | L3MBTL1 (0.34) | L3MBTL1HTR2CSLC6A4CREBBPEP300 | |
| SCHEMBL7945551 | 0.81 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL6618750 | 0.81 | L3MBTL1 (0.42) | L3MBTL1 | |
| SCHEMBL7959273 | 0.80 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL29424477 | 0.76 | KLK7 (0.35) | L3MBTL1HTR2CSLC6A4 | |
| SCHEMBL29424475 | 0.76 | KLK7 (0.35) | L3MBTL1HTR2CSLC6A4 | |
| SCHEMBL1902732 | 0.76 | KLK7 (0.35) | L3MBTL1HTR2CSLC6A4 | |
| SCHEMBL8191113 | 0.76 | PTGER1 (0.33) | HTR2CSLC6A4 | |
| SCHEMBL12154963 | 0.74 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL12154966 | 0.74 | L3MBTL1 (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |
| EP-0983248-A4 | ANALOGS OF DUOCARMYCIN AND CC-1065 | SCRIPPS RESEARCH INST (US) | 2000-09-13 | — | — | EP | disclosed |
| EP-0983248-A1 | ANALOGS OF DUOCARMYCIN AND CC-1065 | The Scripps Research Institute (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052925-A1 | ANALOGS OF DUOCARMYCIN AND CC-1065 | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-11-26 | — | — | WO | disclosed |