Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16300025 | 0.70 | CYP3A4 (0.56) | CYP3A4SHBG | |
| SCHEMBL12162287 | 0.69 | CYP3A4 (0.35) | CYP3A4SHBG | |
| SCHEMBL15195626 | 0.66 | SHBG (0.59) | CYP3A4SHBGPIK3R1PIK3CA | |
| SCHEMBL20347453 | 0.66 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL4234789 | 0.65 | CYP3A4 (0.50) | CYP3A4SHBGPIK3R1PIK3CA | |
| SCHEMBL9974502 | 0.65 | CYP3A4 (0.47) | CYP3A4SHBG | |
| SCHEMBL21029914 | 0.64 | CYP3A4 (0.33) | CYP3A4SHBG | |
| SCHEMBL20278030 | 0.64 | CYP3A4 (0.33) | CYP3A4SHBG | |
| SCHEMBL11960923 | 0.64 | SHBG (0.53) | CYP3A4SHBGPIK3R1PIK3CA | |
| SCHEMBL4227246 | 0.64 | SHBG (0.53) | CYP3A4SHBGPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |