Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942710 | 0.85 | SRC (0.61) | SRC | |
| SCHEMBL7954625 | 0.85 | SRC (0.60) | SRC | |
| SCHEMBL7949094 | 0.82 | SRC (0.60) | SRC | |
| SCHEMBL7952367 | 0.75 | SRC (1.00) | SRC | |
| SCHEMBL8150523 | 0.74 | SRC (0.43) | SRC | |
| SCHEMBL7950799 | 0.73 | SRC (1.00) | SRC | |
| SCHEMBL31060638 | 0.72 | SRC (0.61) | SRC | |
| SCHEMBL3288912 | 0.64 | HDAC1 (0.43) | SRC | |
| SCHEMBL11092917 | 0.62 | ALDH1A1 (0.47) | SRC | |
| SCHEMBL4703615 | 0.60 | ACE (0.47) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |