Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952637 | 0.78 | SRC (0.52) | SRC | |
| SCHEMBL7952620 | 0.74 | SRC (1.00) | SRC | |
| SCHEMBL29941471 | 0.72 | SRC (1.00) | SRC | |
| SCHEMBL7952687 | 0.70 | SRC (0.64) | SRC | |
| SCHEMBL31061145 | 0.63 | SRC (0.61) | SRC | |
| SCHEMBL29941211 | 0.63 | SRC (1.00) | SRC | |
| SCHEMBL7952367 | 0.62 | SRC (1.00) | SRC | |
| SCHEMBL4485378 | 0.60 | APP (0.58) | — | |
| SCHEMBL4471380 | 0.60 | APP (0.64) | — | |
| SCHEMBL7345675 | 0.60 | ACE (0.81) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |