Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952649 | 0.78 | SRC (0.58) | SRC | |
| SCHEMBL7952617 | 0.74 | SRC (0.69) | SRC | |
| SCHEMBL12589541 | 0.65 | XIAP (0.56) | — | |
| SCHEMBL31061145 | 0.62 | SRC (0.61) | SRC | |
| SCHEMBL7341977 | 0.60 | ACE (0.69) | — | |
| SCHEMBL2985314 | 0.60 | RAB9A (0.57) | — | |
| SCHEMBL8363236 | 0.58 | ACE (0.56) | — | |
| SCHEMBL353959 | 0.58 | TDP1 (0.64) | — | |
| SCHEMBL6164081 | 0.58 | TDP1 (0.64) | — | |
| Hydrochloric Acid SCHEMBL7759004 | 0.57 | TDP1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |