Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236429 | 1.00 | EPHX2 (0.47) | EPHX2LOXL2SLC1A3SLC1A2CA1 | |
| SCHEMBL4747242 | 0.83 | MEN1 (0.56) | CA1CA2CA7CA14TERT | |
| SCHEMBL3668459 | 0.83 | CA1 (0.47) | CA1CA2CA7CA14TERT | |
| SCHEMBL8172012 | 0.83 | MEN1 (0.56) | CA1CA2CA7CA14TERT | |
| SCHEMBL7955857 | 0.82 | HPGD (0.54) | MEN1KMT2AANPEP | |
| SCHEMBL4747248 | 0.82 | CYP2C9 (0.53) | EPHX2CA1CA2CA7CA14 | |
| SCHEMBL8164760 | 0.82 | CYP2C9 (0.53) | EPHX2CA1CA2CA7CA14 | |
| Hydrochloric Acid SCHEMBL8614402 | 0.82 | MEN1 (0.55) | CA1CA2CA7CA14TERT | |
| Hydrochloric Acid SCHEMBL8614398 | 0.82 | MEN1 (0.55) | CA1CA2CA7CA14TERT | |
| SCHEMBL3239995 | 0.82 | HPGD (0.54) | MEN1KMT2AANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |