SCHEMBL7955857

SCHEMBL7955857

CC[C@H](C)[C@H](N)C(=O)NCc1ccc(F)cc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.54
GAA P10253 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.49
ANPEP P15144 1/20 0.48
MAPK1 P28482 1/20 0.48
TSHR P16473 1/20 0.48
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3239995 1.00 HPGD (0.54) HPGDGAAL3MBTL1ANPEPMAPK1
SCHEMBL8172012 0.87 MEN1 (0.56) HPGDGAAANPEPTSHRMEN1
SCHEMBL4747242 0.87 MEN1 (0.56) HPGDGAAANPEPTSHRMEN1
SCHEMBL3668459 0.87 CA1 (0.47) ANPEPMEN1KMT2A
SCHEMBL4747248 0.85 CYP2C9 (0.53) HPGDTSHRCARM1PRMT6MEN1
SCHEMBL8164760 0.85 CYP2C9 (0.53) HPGDTSHRCARM1PRMT6MEN1
Hydrochloric Acid SCHEMBL8614398 0.85 MEN1 (0.55) HPGDGAAANPEPTSHRMEN1
Hydrochloric Acid SCHEMBL8614402 0.85 MEN1 (0.55) HPGDGAAANPEPTSHRMEN1
SCHEMBL8155147 0.85 ANPEP (0.57) GAAANPEPMEN1KMT2A
SCHEMBL4746610 0.85 ANPEP (0.57) GAAANPEPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040332-A Succinimide derivative, preparation method and application thereof 遵义医科大学珠海校区 2025-05-27 CN disclosed
CN-118812407-A Succinimide derivative, preparation method and application thereof 遵义医科大学珠海校区 2024-10-22 CN disclosed
WO-2010024772-A1 ASPARTYL PROTEASE INHIBITORS MEDIVIR AB (SE) 2010-03-04 WO disclosed
WO-2008107365-A1 NEW COMPOUNDS MEDIVIR AB (SE) 2008-09-12 WO disclosed