Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955194 | 0.98 | CHRM1 (0.57) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL7952890 | 0.93 | CHRM1 (0.58) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL7954390 | 0.86 | CHRM1 (0.62) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL22488793 | 0.83 | LMNA (0.60) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL22489268 | 0.83 | LMNA (0.60) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL21861228 | 0.83 | CHRM1 (0.55) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL2865466 | 0.81 | LMNA (0.58) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL2864143 | 0.81 | CHRM1 (0.57) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL2859452 | 0.81 | CHRM1 (0.57) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL7956514 | 0.78 | CHRM1 (0.56) | CHRM1CHRM3CHRM2CHRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |