SCHEMBL7953014

SCHEMBL7953014

COc1nc(C)nc(N(C)C(=O)O)n1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CTSK P43235 1/20 0.38
TSHR P16473 4/20 0.37
MAPK1 P28482 1/20 0.37
CASP7 P55210 1/20 0.37
CYP1A2 P05177 1/20 0.37
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GLA P06280 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9027723 0.89 CYP1A2 (0.44) GAAALDH1A1SMN1; SMN2CTSKTSHR
SCHEMBL1111272 0.84 GAA (0.36) GAAALDH1A1SMN1; SMN2CTSKTSHR
SCHEMBL10851912 0.77 GAA (0.36) GAAALDH1A1SMN1; SMN2CTSKTSHR
SCHEMBL13026214 0.75 GAA (0.39) GAAALDH1A1SMN1; SMN2CTSKTSHR
SCHEMBL8795165 0.74 NPSR1 (0.42) ALDH1A1TSHRMAPK1LMNATDP1
SCHEMBL3136168 0.73 HSD17B10 (0.40) ALDH1A1SMN1; SMN2TSHRCYP1A2LMNA
SCHEMBL10415281 0.71 GAA (0.37) GAAALDH1A1
SCHEMBL3789241 0.71 CYP1A2 (0.41) GAAALDH1A1SMN1; SMN2CTSKTSHR
SCHEMBL8503788 0.70 TSHR (0.39) GAAALDH1A1SMN1; SMN2TSHRCYP1A2
SCHEMBL10827038 0.70 KDM4E (0.48) ALDH1A1SMN1; SMN2CYP1A2LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316388-B1 ANTIGROWTH AGENTS FOR PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2001-11-13 US disclosed
US-5847146-A N-heteroartyl-n'-(pyrid-2yl-sulfonyl) ureas, processes for their preparation, and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-12-08 US disclosed
EP-0464838-B1 Substituted sulfonylalkylsulfonylureas, process for their preparation and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-10-07 EP disclosed
EP-0555770-A1 N-Heteroaryl-N'-(pyrid-2-yl-sulfonyl)-ureas, process for their preparation, and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1993-08-18 EP disclosed
US-4746358-A PLANT GROWTH REGULATORS, HERBICIDES; N-TRIAZINYL-AMINOCARBONYL -1,4-BENZODIOXANESULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-24 US disclosed
EP-0101670-B1 PROCESS FOR THE PREPARATION OF HERBICIDES AND PLANT GROWTH REGULATING SULFONYL UREAS CIBA-GEIGY AG (CH) 1988-03-09 EP disclosed
US-4595407-A Triazinyl-amino-carbonyl-1,3-benzohetero- or -1,4-benzohetero-sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-17 US disclosed
EP-0101670-A2 Process for the preparation of herbicides and plant growth regulating sulfonyl ureas CIBA-GEIGY AG (CH) 1984-02-29 EP disclosed