SCHEMBL3136168

SCHEMBL3136168

CN(C(=O)O)c1nc(N(C)C(=O)O)nc(N(C)C(=O)O)n1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.40
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
CREBBP Q92793 1/20 0.40
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10677143 0.81 SMN1; SMN2 (0.44) HSD17B10LMNAHPGDALDH1A1KDM4E
Hydrochloric Acid SCHEMBL11800735 0.79 SMN1; SMN2 (0.42) HSD17B10LMNAHPGDALDH1A1KDM4E
SCHEMBL9027723 0.79 CYP1A2 (0.44) LMNACYP1A2ALDH1A1SMN1; SMN2TSHR
SCHEMBL10827038 0.76 KDM4E (0.48) LMNACYP1A2POLBALDH1A1KDM4E
SCHEMBL6500461 0.76 KDM4E (0.40) HSD17B10LMNABLMPOLBALDH1A1
SCHEMBL7953014 0.73 GAA (0.39) LMNACYP1A2ALDH1A1SMN1; SMN2TSHR
SCHEMBL2575372 0.73 PLK1 (0.33) LMNAPOLBHPGDTSHR
SCHEMBL5159200 0.72 KDM4E (0.38) HSD17B10HPGDALDH1A1KDM4ESMN1; SMN2
Altretamine SCHEMBL28503842 0.71 LMNA (0.65) HSD17B10LMNACYP1A2THRBBLM
SCHEMBL9132750 0.70 LMNA (0.55) HSD17B10LMNACYP1A2THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7641813-B2 protect metals from corrosion and are effective in preventing hard water deposits; comprising water soluble liquid alcohol freezing point depressants ethylene glycol, 2,4,6-tris(5-carboxypentylamino)-1,3,5-triazine, a mixture of tolutriazole compounds, 2-ethylhexanoic acid, heptanoic acid CIBA CORPORATION (US) 2010-01-05 US claimed
WO-2009043814-A1 ANTIFREEZE COMPOSITIONS BASF SE (CH) 2009-04-09 WO claimed
US-20090090887-A1 Antifreeze compositions CIBA CORP. 2009-04-09 US claimed
US-7641813-B2 protect metals from corrosion and are effective in preventing hard water deposits; comprising water soluble liquid alcohol freezing point depressants ethylene glycol, 2,4,6-tris(5-carboxypentylamino)-1,3,5-triazine, a mixture of tolutriazole compounds, 2-ethylhexanoic acid, heptanoic acid CIBA CORPORATION (US) 2010-01-05 US disclosed
WO-2009043814-A1 ANTIFREEZE COMPOSITIONS BASF SE (CH) 2009-04-09 WO disclosed
US-20090090887-A1 Antifreeze compositions CIBA CORP. 2009-04-09 US disclosed
US-5549847-A STIRRING A FILTER CAKE OF CORROSION INHIBITOR WITH DISPERSANT AND THICKENER; STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1996-08-27 US disclosed
EP-0511163-B1 Pourable aqueous dispersions of polycarboxylic acid corrosion inhibitors CIBA GEIGY AG (CH) 1995-07-26 EP disclosed
EP-0553962-A1 Corrosion inhibiting compositions CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
EP-0511163-A1 Pourable aqueous dispersions of polycarboxylic acid corrosion inhibitors CIBA-GEIGY AG (CH) 1992-10-28 EP disclosed
US-5076951-A Hydrolyzed copolymer of maleic anhydride with ethyleneically u nsaturated monomer, corosion inhibitor, polyhyrdric alcohol CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0398284-A1 Antifreeze compositions CIBA-GEIGY AG (CH) 1990-11-22 EP disclosed
EP-0046139-B1 USE OF TRIAZINE-CARBOXYLIC ACIDS AS CORROSION INHIBITORS FOR AQUEOUS SYSTEMS CIBA-GEIGY AG (CH) 1984-07-18 EP disclosed
US-4402907-A Triazine carboxylic acids as corrosion inhibitors for aqueous systems CIBA-GEIGY CORPORATION (US) 1983-09-06 US disclosed
EP-0046139-A1 Use of triazine-carboxylic acids as corrosion inhibitors for aqueous systems CIBA-GEIGY AG (CH) 1982-02-17 EP disclosed