Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.79 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.79 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.63 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421882 | 0.92 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL22029436 | 0.89 | ITGB3 (0.85) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL22029510 | 0.89 | ITGB3 (0.85) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL6359531 | 0.88 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL6421564 | 0.88 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL6421303 | 0.88 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL5301316 | 0.84 | ITGAV (0.77) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL5301326 | 0.84 | ITGAV (0.77) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL7447983 | 0.83 | ITGAV (0.85) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7439077 | 0.83 | ITGAV (0.85) | ITGAVITGB3ITGB6ITGB8ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297249-B1 | SUBSTITUTED 2-CARBOXYALKYLPYRIDINES | MERCK & CO., INC. | 2001-10-02 | — | — | US | disclosed |