Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306078 | 0.98 | ACE (0.47) | BACE1ACEOPRD1OPRM1OPRK1 | |
| SCHEMBL11306085 | 0.98 | ACE (0.47) | BACE1ACEOPRD1OPRM1OPRK1 | |
| SCHEMBL29662320 | 0.92 | OPRD1 (0.48) | ACEOPRD1OPRM1OPRK1MME | |
| SCHEMBL25389470 | 0.92 | CTSC (0.48) | ACEOPRD1OPRM1OPRK1MME | |
| SCHEMBL25389475 | 0.92 | CTSC (0.48) | ACEOPRD1OPRM1OPRK1MME | |
| SCHEMBL30751950 | 0.89 | NAALAD2 (0.51) | ACEOPRD1OPRM1OPRK1MME | |
| SCHEMBL31474554 | 0.88 | BACE1 (0.56) | BACE1CTSDMME | |
| SCHEMBL29590749 | 0.88 | OPRD1 (0.48) | BACE1OPRD1OPRM1OPRK1 | |
| SCHEMBL31094953 | 0.87 | NAALAD2 (0.60) | BACE1CTSD | |
| SCHEMBL30578452 | 0.87 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068295-A1 | CELL DIFFERENTIATION/PROLIFERATION AND MAINTENANCE FACTOR AND USES THEREOF | BresaGen Limited (AU) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999053021-A9 | CELL DIFFERENTIATION/PROLIFERATION AND MAINTENANCE FACTOR AND USES THEREOF | BRESAGEN LTD (AU) | 2000-05-04 | — | — | WO | disclosed |
| WO-1999053021-A1 | CELL DIFFERENTIATION/PROLIFERATION AND MAINTENANCE FACTOR AND USES THEREOF | BRESAGEN LIMITED (AU) | 1999-10-21 | — | — | WO | disclosed |