SCHEMBL7953671

SCHEMBL7953671

O=C(O)C1(CC2(C(=O)O)c3ccccc3C=CC2O)c2ccccc2C=CC1O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.35
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28954161 0.78 THRB (0.36) KIF11ALDH1A1NPSR1THRBTDP1
SCHEMBL7567336 0.77 THRB (0.39) KIF11ALDH1A1NPSR1THRBTDP1
SCHEMBL9437383 0.73 THRB (0.33) ALDH1A1NPSR1THRBTDP1HTT
SCHEMBL6544863 0.70 KDM4E (0.35)
SCHEMBL31286204 0.70 KDM4E (0.35)
SCHEMBL15716844 0.68 PDK2 (0.34) KMT2A
SCHEMBL20036246 0.68 CACNB4 (0.34)
SCHEMBL7525101 0.67 KDM4E (0.33)
SCHEMBL6545025 0.67 KDM4E (0.37) KIF11
SCHEMBL6545414 0.67 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271255-B1 USEFUL AS ANTIBACTERIAL AND ANTIPROTOZOAL AGENTS IN INFECTIONS IN MAMMALS, FISH, AND BIRDS BIOTICA TECHNOLOGY LIMITED (GB) 2001-08-07 US disclosed