Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442796 | 0.95 | SIGMAR1 (0.55) | MCHR1ADRA1ATMEM97SIGMAR1 | |
| SCHEMBL7431164 | 0.89 | OPRL1 (0.57) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL4232283 | 0.88 | TMEM97 (0.56) | MCHR1ADRA1ATMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11831622 | 0.87 | TMEM97 (0.55) | MCHR1ADRA1ATMEM97SIGMAR1 | |
| SCHEMBL8001398 | 0.81 | SIGMAR1 (0.53) | TMEM97SIGMAR1 | |
| SCHEMBL14273906 | 0.81 | OPRL1 (0.67) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL7431676 | 0.80 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL14273974 | 0.79 | OPRL1 (0.65) | MCHR1ADRA1AOPRL1TMEM97SIGMAR1 | |
| SCHEMBL11932470 | 0.77 | GRIN1 (0.58) | OPRL1 | |
| SCHEMBL8012780 | 0.77 | GRIN1 (0.66) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | disclosed |