Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956527 | 0.98 | KMT2A (0.67) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7966210 | 0.95 | TSHR (0.63) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7952958 | 0.91 | MEN1 (0.60) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7954452 | 0.86 | NPSR1 (0.67) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7959716 | 0.85 | HCRTR1 (0.73) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL5083225 | 0.85 | KMT2A (0.73) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9425861 | 0.85 | MEN1 (0.68) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL19248825 | 0.85 | KMT2A (0.68) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL28907971 | 0.85 | MEN1 (0.68) | NPSR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7956531 | 0.85 | KMT2A (0.68) | NPSR1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |