Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954446 | 0.95 | NPSR1 (0.65) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL7956527 | 0.94 | KMT2A (0.67) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL7952958 | 0.92 | MEN1 (0.60) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL7959716 | 0.87 | HCRTR1 (0.73) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL7966214 | 0.86 | ALDH1A1 (0.61) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL10257995 | 0.86 | MEN1 (0.68) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL50006 | 0.83 | LMNA (0.64) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11331258 | 0.83 | ALDH1A1 (0.78) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11052364 | 0.82 | LMNA (0.62) | TSHRALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9898531 | 0.82 | LMNA (0.66) | TSHRALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |