Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.50 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.50 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.50 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956498 | 0.99 | KDM4E (0.54) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL30716629 | 0.89 | MEN1 (0.48) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL9275434 | 0.88 | KDM4E (0.60) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL7954459 | 0.87 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28575933 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28366897 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL27761606 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL31396225 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL1865526 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28371003 | 0.86 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |