Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945983 | 0.99 | PTGS2 (0.67) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL7954996 | 0.96 | PTGS2 (0.66) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL11327527 | 0.91 | PTGS2 (0.71) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL9446603 | 0.91 | PTGS2 (0.75) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL12715080 | 0.91 | PTGS2 (0.75) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL7954437 | 0.90 | PTGS2 (0.61) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL11985699 | 0.90 | PTGS2 (0.72) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL27528077 | 0.87 | TSHR (0.71) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL16193364 | 0.87 | PTGS2 (0.70) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL11985691 | 0.86 | PTGS2 (0.68) | PTGS2HSD17B10KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |