Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663729 | 0.84 | MAPT (0.69) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL6796229 | 0.82 | MAPT (0.62) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL2090419 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL2090421 | 0.82 | ATM (0.58) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL2089843 | 0.82 | POLB (0.56) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL2089842 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL1233566 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL7955066 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2MAPTATML3MBTL1 | |
| SCHEMBL4035376 | 0.80 | PSMB11 (0.57) | ALDH1A1SMN1; SMN2MAPTATMPOLB | |
| SCHEMBL19454815 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPTATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |