Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MANBA | O00462 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236497 | 1.00 | KMT2A (0.43) | KMT2AMANBALMNATHRBHIF1A | |
| SCHEMBL3265510 | 0.88 | POLB (0.40) | KMT2AMANBALMNATHRBHIF1A | |
| SCHEMBL7955722 | 0.88 | POLB (0.40) | KMT2AMANBALMNATHRBHIF1A | |
| Hydrochloric Acid SCHEMBL291832 | 0.83 | KMT2A (0.44) | KMT2AMEN1HTTSMN1; SMN2CYP2C9 | |
| SCHEMBL8149511 | 0.79 | LMNA (0.42) | MANBALMNATHRBHIF1A | |
| SCHEMBL4749440 | 0.79 | LMNA (0.42) | MANBALMNATHRBHIF1A | |
| SCHEMBL12239952 | 0.75 | LMNA (0.46) | MANBALMNATHRBHIF1A | |
| SCHEMBL7153061 | 0.75 | LMNA (0.46) | MANBALMNATHRBHIF1A | |
| SCHEMBL7150023 | 0.75 | LMNA (0.46) | MANBALMNATHRBHIF1A | |
| SCHEMBL7150099 | 0.75 | LMNA (0.46) | MANBALMNATHRBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |