Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795495 | 1.00 | EPHX1 (0.48) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL11828128 | 0.80 | SLC6A2 (0.50) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL11828122 | 0.80 | SLC6A2 (0.50) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL902546 | 0.79 | EPHX1 (0.61) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL902538 | 0.79 | EPHX1 (0.61) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL2736329 | 0.79 | EPHX1 (0.61) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL7307677 | 0.79 | EPHX1 (0.61) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL795585 | 0.79 | DPP4 (0.37) | TAAR1 | |
| SCHEMBL795583 | 0.79 | DPP4 (0.37) | TAAR1 | |
| SCHEMBL12491357 | 0.78 | MAOB (0.54) | EPHX1SLC6A2TAAR1MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616056-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | Neuroquest Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034232-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | NEUROQUEST INC. (CA) | 2012-03-22 | — | — | WO | disclosed |