Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795583 | 1.00 | DPP4 (0.37) | DPP4F2TAAR1AOC3HTR2A | |
| SCHEMBL6944728 | 0.80 | DPP4 (0.46) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL23934880 | 0.80 | DPP4 (0.46) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL795495 | 0.79 | EPHX1 (0.48) | TAAR1 | |
| SCHEMBL795497 | 0.79 | EPHX1 (0.48) | TAAR1 | |
| SCHEMBL1101279 | 0.79 | DPP4 (0.41) | DPP4F2TAAR1AOC3HTR2A | |
| SCHEMBL27082226 | 0.76 | TAAR1 (0.44) | DPP4F2TAAR1AOC3HTR2A | |
| SCHEMBL8034429 | 0.75 | DPP4 (0.41) | DPP4F2TAAR1HTR2AADRA2A | |
| SCHEMBL8034426 | 0.75 | DPP4 (0.41) | DPP4F2TAAR1HTR2AADRA2A | |
| SCHEMBL4751156 | 0.72 | HRH1 (0.47) | TAAR1HTR2AADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616056-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | Neuroquest Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034232-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | NEUROQUEST INC. (CA) | 2012-03-22 | — | — | WO | disclosed |