Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.52 |
| ▸ | MEN1 | O00255 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954783 | 0.89 | HCAR2 (0.57) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1954102 | 0.88 | ANO1 (0.61) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1954819 | 0.88 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1952340 | 0.85 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL12271471 | 0.85 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1954767 | 0.85 | RAB9A (0.55) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1954403 | 0.83 | ANO1 (0.60) | ANO1 | |
| SCHEMBL1951853 | 0.83 | ANO1 (0.51) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL3628782 | 0.83 | MEN1 (0.49) | KMT2AMEN1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL1953118 | 0.82 | ANO1 (0.58) | KMT2AMEN1ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |