SCHEMBL7955137

SCHEMBL7955137

CN1C(=O)C[C@H](O)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5427936 1.00
SCHEMBL4711905 1.00
SCHEMBL19711770 0.74 KMT2A (0.47)
SCHEMBL22045856 0.74 KMT2A (0.47)
SCHEMBL4181392 0.72
SCHEMBL2021592 0.72
SCHEMBL3255643 0.72
SCHEMBL9708934 0.72
SCHEMBL10182573 0.72
SCHEMBL23697812 0.72 CYP19A1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494106-B1 PROCESSES FOR MAKING, AND METHODS OF USING, GLYCOPYRRONIUM COMPOUNDS JOURNEY MEDICAL CORP (US) 2022-07-20 EP disclosed
US-11352323-B2 Processes for making, and methods of using, glycopyrronium compounds JOURNEY MEDICAL CORPORATION (US) 2022-06-07 US disclosed
US-20210130289-A1 PROCESSES FOR MAKING, AND METHODS OF USING, GLYCOPYRRONIUM COMPOUNDS SWK FUNDING LLC 2021-05-06 US disclosed
US-10906871-B2 Processes for making, and methods of using, glycopyrronium compounds DERMIRA, INC. (US) 2021-02-02 US disclosed
US-20190161443-A1 PROCESSES FOR MAKING, AND METHODS OF USING, GLYCOPYRRONIUM COMPOUNDS SWK FUNDING LLC 2019-05-30 US disclosed
US-9630934-B2 Fumarate compounds, pharmaceutical compositions thereof, and methods of use Nguyen, Mark Quang (US) 2017-04-25 US disclosed
EP-2885294-B1 SYNTHESIS OF AN ANTIVIRAL COMPOUND GILEAD SCIENCES INC (US) 2016-11-30 EP disclosed
WO-2016127186-A1 FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE NGUYEN MARK QUANG (US) 2016-08-11 WO disclosed
US-20160229819-A1 FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE Nguyen, Mark Quang (US) 2016-08-11 US disclosed
US-9045462-B2 Synthesis of an antiviral compound GILEAD SCIENCES, INC. (US) 2015-06-02 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
US-5266728-A Method for producing optically active 3-substituted-2-norbornanones and their intermediates CHISSO CORPORATION (JP) 1993-11-30 US disclosed
EP-0528694-A2 Method for producing optically active 3-substituted-2-norbornanones and their intermediates CHISSO CORPORATION (JP) 1993-02-24 EP disclosed
US-4812565-A ANTIHISTAMINE INTERMEDIATES A. H. ROBINS COMPANY, INCORPORATED (US) 1989-03-14 US disclosed
US-4810795-A ANTIHISTAMINES A. H. ROBINS COMPANY, INCORPORATED (US) 1989-03-07 US disclosed
US-4727152-A Intermediates useful in the preparation of fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof A. H. ROBINS COMPANY, INC. (US) 1988-02-23 US disclosed
US-4705853-A ANTIHISTAMINES A. H. ROBINS COMPANY, INC. (US) 1987-11-10 US disclosed
US-4642343-A ANTIHISTAMINES A. H. ROBINS COMPANY, INCORPORATED (US) 1987-02-10 US disclosed
US-4604388-A Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof in a method of counteracting histamine A. H. ROBINS COMPANY, INCORPORATED (US) 1986-08-05 US disclosed
US-4592866-A Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof A. H. ROBINS COMPANY, INC. (US) 1986-06-03 US disclosed