Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 4/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955153 | 1.00 | MMP1 (0.40) | MMP1MMP13ECE1MMP3FAAH | |
| SCHEMBL7838068 | 1.00 | MMP1 (0.40) | MMP1MMP13ECE1MMP3FAAH | |
| SCHEMBL7837906 | 0.88 | MMP1 (0.46) | MMP1MMP13MMP3APPMMP8 | |
| SCHEMBL7957317 | 0.88 | MMP1 (0.46) | MMP1MMP13MMP3APPMMP8 | |
| SCHEMBL7838493 | 0.88 | MMP1 (0.46) | MMP1MMP13MMP3APPMMP8 | |
| SCHEMBL7838489 | 0.88 | MMP1 (0.46) | MMP1MMP13MMP3APPMMP8 | |
| SCHEMBL7960498 | 0.84 | MMP1 (0.40) | MMP1MMP13MMP3FAAHMMP8 | |
| SCHEMBL7960499 | 0.84 | MMP1 (0.40) | MMP1MMP13MMP3FAAHMMP8 | |
| SCHEMBL7960494 | 0.84 | MMP1 (0.40) | MMP1MMP13MMP3FAAHMMP8 | |
| SCHEMBL7960600 | 0.83 | MMP1 (0.37) | MMP1MMP13MMP3FAAHAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281363-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; AUTOIMMUNE DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |