Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 20/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955315 | 1.00 | ADRA1D (0.57) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7944685 | 0.90 | ADRA1D (0.55) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7953201 | 0.89 | ADRA1D (0.54) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7944541 | 0.89 | ADRA1D (0.54) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7952661 | 0.79 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6718413 | 0.77 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6767632 | 0.76 | ADRA1D (0.67) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7952658 | 0.76 | ADRA1D (0.57) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7953225 | 0.75 | ADRA1D (0.49) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7958027 | 0.74 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228861-B1 | BENIGN PROSTATIC HYPERPLASIA; ANTICHOLESTEROL AGENTS; IMPOTENCY; INTRAOCULAR PRESSURE; ANTIARRHYTHMIA AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-08 | — | — | US | disclosed |
| US-6172066-B1 | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-01-09 | — | — | US | disclosed |