Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 3/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955444 | 1.00 | NT5E (0.50) | NT5ESLC6A2TYMPSSTR5HPSE | |
| SCHEMBL8317663 | 0.94 | NT5E (0.52) | NT5ESLC6A2TYMPSSTR5HPSE | |
| SCHEMBL7957678 | 0.94 | NT5E (0.52) | NT5ESLC6A2TYMPSSTR5HPSE | |
| SCHEMBL7958046 | 0.91 | NT5E (0.44) | NT5ETYMPHPSENPC1RAB9A | |
| SCHEMBL8316593 | 0.90 | NT5E (0.48) | NT5ESLC6A2TYMPSSTR5HTT | |
| SCHEMBL7962356 | 0.90 | NT5E (0.48) | NT5ESLC6A2TYMPSSTR5HTT | |
| SCHEMBL7957807 | 0.88 | TYMP (0.38) | NT5ETYMPHPSE | |
| SCHEMBL7948338 | 0.88 | NT5E (0.39) | NT5ETYMPHPSE | |
| SCHEMBL7957682 | 0.87 | NT5E (0.54) | NT5ESSTR5HPSEHTTNPC1 | |
| SCHEMBL7962368 | 0.86 | TYR (0.42) | NT5ETYMPHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |