Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 10/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | SDHA | P31040 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CALML3 | P27482 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156352 | 0.89 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8308401 | 0.88 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8308403 | 0.88 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL27552994 | 0.87 | MAOB (0.79) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6162190 | 0.86 | F10 (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL18408933 | 0.86 | MAOB (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL18408943 | 0.86 | MAOB (0.77) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7955695 | 0.84 | MAOB (0.66) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7955698 | 0.84 | MAOB (0.66) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL18410481 | 0.84 | MAOB (0.72) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255304-B1 | AIDS THERAPY | PHARMACIA & UPJOHN COMPANY | 2001-07-03 | — | — | US | claimed |