Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17009347 | 0.86 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL6127110 | 0.86 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL6122200 | 0.86 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL4698443 | 0.86 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL20530282 | 0.86 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL6127212 | 0.86 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL7901816 | 0.85 | POLB (0.45) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL2357742 | 0.84 | FOLH1 (0.47) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL7900077 | 0.84 | HPGD (0.44) | HPGDPOLBSMN1; SMN2NPC1TP53 | |
| SCHEMBL6127104 | 0.83 | POLB (0.46) | HPGDPOLBSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262084-B1 | Compounds that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION | 2001-07-17 | — | — | US | claimed |
| US-6262084-B1 | Compounds that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION | 2001-07-17 | — | — | US | disclosed |