Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | TOP1 | P11387 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ARG2 | P78540 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1436 | 0.93 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL6280201 | 0.93 | MAOB (0.75) | MAOBTOP1CA1CA2ARG2 | |
| Water SCHEMBL3478300 | 0.91 | MAOB (0.71) | MAOBTOP1CA1CA2ARG2 | |
| Hydrochloric Acid SCHEMBL5137799 | 0.91 | MAOB (0.71) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL5956337 | 0.84 | MAOB (0.68) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL11509823 | 0.83 | HTR2A (0.50) | MAOBAOC3LOXL2HTR2ACYP2A6 | |
| SCHEMBL11509821 | 0.83 | HTR2A (0.50) | MAOBAOC3LOXL2HTR2ACYP2A6 | |
| SCHEMBL3288071 | 0.81 | MAOB (0.62) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL155055 | 0.81 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 | |
| SCHEMBL1524697 | 0.81 | MAOB (1.00) | MAOBTOP1CA1CA2ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616056-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | Neuroquest Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034232-A1 | TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS | NEUROQUEST INC. (CA) | 2012-03-22 | — | — | WO | disclosed |