SCHEMBL1436

SCHEMBL1436

NCC=CCc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.75
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ARG2 P78540 1/20 0.50
AOC3 Q16853 1/20 0.48
LOXL2 Q9Y4K0 2/20 0.48
TOP1 P11387 1/20 0.46
HTR2A P28223 3/20 0.44
CYP2A6 P11509 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
IDO1 P14902 1/20 0.42
AGXT P21549 1/20 0.41
KCNH2 Q12809 2/20 0.40
MAOA P21397 1/20 0.39
CALM1 P0DP23 1/20 0.39
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280201 1.00 MAOB (0.75) MAOBCA1CA2ARG2AOC3
Water SCHEMBL3478300 0.98 MAOB (0.71) MAOBCA1CA2ARG2AOC3
Hydrochloric Acid SCHEMBL5137799 0.98 MAOB (0.71) MAOBCA1CA2ARG2AOC3
SCHEMBL795584 0.93 MAOB (0.65) MAOBCA1CA2ARG2AOC3
SCHEMBL155055 0.87 MAOB (1.00) MAOBCA1CA2ARG2LOXL2
SCHEMBL1524697 0.87 MAOB (1.00) MAOBCA1CA2ARG2LOXL2
SCHEMBL155054 0.87 MAOB (1.00) MAOBCA1CA2ARG2LOXL2
SCHEMBL5489486 0.83 MAOB (0.50) MAOBCA1CA2ARG2AOC3
SCHEMBL5956337 0.81 MAOB (0.68) MAOBCA1CA2ARG2LOXL2
SCHEMBL3288071 0.78 MAOB (0.62) MAOBCA1CA2ARG2LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180359854-A1 POPULATION OF METAL OXIDE NANOSHEETS, PREPARATION METHOD THEREOF, AND ELECTRICAL CONDUCTOR AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2018-12-13 US claimed
EP-1189622-B1 ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS GENZYME CORP (US) 2007-07-25 EP claimed
EP-1800687-A2 Anionic polymers as toxin binders and antibacterial agents GENZYME CORPORATION (US) 2007-06-27 EP claimed
US-6890523-B2 Anionic polymers as toxin binders and antibacterial agents GENZYME CORPORATION (US) 2005-05-10 US claimed
EP-1014999-B1 CATIONIC POLYMERS AS TOXIN-BINDING AGENTS GENZYME CORP (US) 2004-12-08 EP claimed
US-20030138397-A1 Anionic polymers as toxin binders and antibacterial agents GELTEX PHARMACEUTICALS, INC. 2003-07-24 US claimed
JP-2002544226-A 2002-12-24 JP claimed
EP-1189622-A2 ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS Geltex Pharmaceuticals, Inc. (US) 2002-03-27 EP claimed
US-20010041171-A1 Anionic polymers as toxin binders GELTEX PHARMACEUTICALS, INC. (US) 2001-11-15 US claimed
US-6270755-B1 POLYMER COMPRISING PENDANT ACID FUNCTIONAL GROUPS OR A SALT THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE CATION, SAID POLYMER COMPRISING NO ACID ANHYDRIDE GROUPS. GELTEX PHARMACEUTICALS, INC. 2001-08-07 US claimed
WO-1999015186-A1 CATIONIC POLYMERS AS TOXIN-BINDING AGENTS GELTEX PHARMACEUTICALS, INC. (US) 1999-04-01 WO claimed
US-5411845-A Coatings for light sensitive photographic film elements IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-05-02 US claimed
EP-0277894-B1 PROCESS FOR THE PREPARATION OF TRIALKOXYBENZALDEHYDE RHONE-POULENC CHIMIE (FR) 1992-01-29 EP claimed
US-4933498-A HYDROLYZING BROMO-HYDROXY-METHOXY BENZALDEHYDE, DIRECTLY ETHERIFYING WITH A LOWER ALKYL HALIDE RHONE-POULENC CHIMIE (FR) 1990-06-12 US claimed
EP-0277894-A2 Process for the preparation of trialkoxybenzaldehyde RHONE-POULENC CHIMIE (FR) 1988-08-10 EP claimed
US-4754089-A SEPARATION OF PHASE BY PERMEABLE MEMBRANE SEPRACOR INC. (US) 1988-06-28 US claimed
US-4644042-A USING WATER SOLUBLE FREE RADICAL POLYMERIZATION CATALYST NITTO BOSEKI CO., LTD. (JP) 1987-02-17 US claimed
EP-0173963-A2 Polymers of n-substituted secondary monoallylamines and their salts and process for producing the same NITTO BOSEKI CO., LTD. (JP) 1986-03-12 EP claimed
EP-0066103-B1 PROCESS FOR THE REDUCTION OF REDUCIBLE GROUPS, AND ITS APPLICATION Eckert, Heiner, dr. (DE) 1985-08-28 EP claimed
US-4299911-A POLYMER CONTAINING AN ETHYLENICALLY UNSATURATED DOUBLE BOND SOMAR MANUFACTURING CO., LTD. (JP) 1981-11-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010041171-A1 Anionic polymers as toxin binders PIGS, CD47, BTD MAOB 2782/4885CA1 748/4885CA2 1578/4885
US-20030138397-A1 Anionic polymers as toxin binders and antibacterial agents MSN, ANTXR2, PNKP MAOB 2903/4885CA1 2335/4885CA2 2499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.