Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210064 | 0.73 | MAPT (0.42) | POLBCYP3A4CYP2D6PORCNMEN1 | |
| SCHEMBL5770174 | 0.73 | LMNA (0.41) | POLBCYP3A4CYP2D6PORCNMEN1 | |
| SCHEMBL5210386 | 0.71 | MAPT (0.38) | POLBCYP3A4CYP2D6PORCNMEN1 | |
| SCHEMBL5245911 | 0.70 | CHRM1 (0.39) | CYP3A4CYP2D6PORCNMEN1LMNA | |
| SCHEMBL5210390 | 0.70 | MAPT (0.41) | CYP3A4CYP2D6PORCNMEN1LMNA | |
| SCHEMBL10902060 | 0.70 | F10 (0.57) | CYP3A4CYP2D6PORCNMEN1MAPT | |
| SCHEMBL11687763 | 0.69 | TRPV1 (0.48) | CYP2D6MEN1LMNAMAPK1KMT2A | |
| SCHEMBL1363284 | 0.68 | KCNH2 (0.34) | CYP3A4CYP2D6LMNA | |
| SCHEMBL10903822 | 0.67 | F10 (0.60) | CYP3A4CYP2D6PORCNLMNAMAPK1 | |
| SCHEMBL7463020 | 0.67 | RXFP1 (0.39) | CYP3A4CYP2D6MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177452-B1 | ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-23 | — | — | US | disclosed |