Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 1.00 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618490 | 1.00 | PRCP (1.00) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL11842693 | 1.00 | PRCP (1.00) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL2792169 | 1.00 | PRCP (1.00) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL5898619 | 1.00 | PRCP (1.00) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL2983853 | 1.00 | PRCP (1.00) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL9825221 | 1.00 | PRCP (1.00) | PRCPTLR2NAAAGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL9275753 | 0.98 | PRCP (0.97) | PRCPTLR2NAAAGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL11789753 | 0.98 | PRCP (0.97) | PRCPTLR2NAAAGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL7769069 | 0.98 | PRCP (0.97) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL23762418 | 0.98 | PRCP (0.97) | PRCPTLR2NAAAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305492-A4 | PHOSPHOLIPASE A 2? INHIBITORS | — | 1991-09-04 | — | — | EP | claimed |
| EP-0305492-A1 | PHOSPHOLIPASE A 2? INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-08 | — | — | EP | claimed |
| WO-1988006885-A1 | PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-22 | — | — | WO | claimed |
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | disclosed |
| EP-0923546-A1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | Merckle GmbH (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998005637-A1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A¿2? | MERCKLE GMBH (DE) | 1998-02-12 | — | — | WO | disclosed |
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |
| EP-0305492-A4 | PHOSPHOLIPASE A 2? INHIBITORS | — | 1991-09-04 | — | — | EP | disclosed |
| EP-0305492-A1 | PHOSPHOLIPASE A 2? INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4792555-A | DESENSITIZERS; ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| WO-1988006885-A1 | PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-22 | — | — | WO | disclosed |