SCHEMBL16618490

SCHEMBL16618490

CCCCCCCCCCCCCCCCCCNC(=O)C1CCCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 1.00
TLR2 O60603 2/20 0.60
NAAA Q02083 1/20 0.58
GNAI3 P08754 1/20 0.57
GNAO1 P09471 1/20 0.57
GNAI1 P63096 1/20 0.57
DPP7 Q9UHL4 1/20 0.53
EPHX1 P07099 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11842693 1.00 PRCP (1.00) PRCPTLR2NAAAGNAI3GNAO1
SCHEMBL2792169 1.00 PRCP (1.00) PRCPTLR2NAAAGNAI3GNAO1
SCHEMBL7955918 1.00 PRCP (1.00) PRCPTLR2NAAAGNAI3GNAO1
SCHEMBL5898619 1.00 PRCP (1.00) PRCPTLR2NAAAGNAI3GNAO1
SCHEMBL2983853 1.00 PRCP (1.00) PRCPTLR2NAAAGNAI3GNAO1
SCHEMBL9825221 1.00 PRCP (1.00) PRCPTLR2NAAAGNAI3GNAO1
Hydrochloric Acid SCHEMBL9275753 0.98 PRCP (0.97) PRCPTLR2NAAAGNAI3GNAO1
Hydrochloric Acid SCHEMBL11789753 0.98 PRCP (0.97) PRCPTLR2NAAAGNAI3GNAO1
Hydrochloric Acid SCHEMBL7769069 0.98 PRCP (0.97) PRCPTLR2NAAAGNAI3GNAO1
SCHEMBL23762418 0.98 PRCP (0.97) PRCPTLR2NAAAGNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3057444-A1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES Givaudan SA (CH) 2016-08-24 EP claimed
US-20160227825-A1 Organic Compounds having Taste-Modifying Properties GIVAUDAN SA (CH) 2016-08-11 US claimed
WO-2015048991-A1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES GIVAUDAN SA (CH) 2015-04-09 WO claimed
US-11834393-B2 Organic compounds having taste-modifying properties GIVAUDAN SA (CH) 2023-12-05 US disclosed
US-20210147345-A1 Organic Compounds having Taste-Modifying Properties GIVAUDAN SA (CH) 2021-05-20 US disclosed
CN-105592720-B Organic compounds with taste-improving properties 奇华顿股份有限公司 2020-07-07 CN disclosed
EP-3057444-B1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES GIVAUDAN SA (CH) 2017-12-06 EP disclosed
EP-3057444-A1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES Givaudan SA (CH) 2016-08-24 EP disclosed
US-20160227825-A1 Organic Compounds having Taste-Modifying Properties GIVAUDAN SA (CH) 2016-08-11 US disclosed
CN-105592720-A Organic compounds having taste-modifying properties GIVAUDAN SA 2016-05-18 CN disclosed
WO-2015048991-A1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES GIVAUDAN SA (CH) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160227825-A1 Organic Compounds having Taste-Modifying Properties TAS2R5, TAS2R3, TAS2R1 PRCP 3688/4885TLR2 3408/4885NAAA 2832/4885
US-11834393-B2 Organic compounds having taste-modifying properties TAS2R5, TAS2R3, TAS2R1 PRCP 3688/4885TLR2 3408/4885NAAA 2832/4885
US-20210147345-A1 Organic Compounds having Taste-Modifying Properties TAS2R5, TAS2R3, TAS2R1 PRCP 3688/4885TLR2 3408/4885NAAA 2832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.