Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961310 | 0.92 | KDM4E (0.37) | MEN1KMT2AHCRTR1GAALMNA | |
| SCHEMBL7956188 | 0.88 | ALDH1A1 (0.38) | MEN1KMT2ALMNASMN1; SMN2THRB | |
| SCHEMBL7956396 | 0.88 | PDE4A (0.39) | MEN1KMT2AHCRTR1GAAPDE4A | |
| SCHEMBL7961451 | 0.82 | MEN1 (0.37) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL6993981 | 0.81 | KCNH2 (0.37) | LMNASMN1; SMN2THRBHTT | |
| SCHEMBL7954561 | 0.81 | MEN1 (0.40) | MEN1KMT2AHCRTR1GAACCR3 | |
| SCHEMBL7956429 | 0.78 | MEN1 (0.39) | MEN1KMT2AHCRTR1GAALMNA | |
| SCHEMBL7955948 | 0.78 | MEN1 (0.36) | MEN1KMT2AHCRTR1GAACCR3 | |
| SCHEMBL7958680 | 0.78 | KMT2A (0.41) | MEN1KMT2AHCRTR1PDE4APDE4B | |
| SCHEMBL7947325 | 0.78 | PDE4A (0.40) | MEN1KMT2AHCRTR1GAAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |