Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209979 | 0.91 | GPR52 (0.61) | GPR52S1PR5S1PR4SLC9A1KDM1A | |
| SCHEMBL1852510 | 0.88 | GPR52 (0.57) | GPR52S1PR5S1PR4SLC9A1KDM1A | |
| SCHEMBL7957517 | 0.86 | GPR52 (0.62) | GPR52S1PR5S1PR4KDM1A | |
| SCHEMBL3223348 | 0.85 | GPR52 (0.52) | GPR52S1PR5S1PR4SLC9A1 | |
| SCHEMBL1852836 | 0.83 | GPR52 (0.58) | GPR52S1PR5S1PR4SLC9A1KDM1A | |
| SCHEMBL1851699 | 0.82 | GPR52 (0.52) | GPR52S1PR5S1PR4SLC9A1 | |
| SCHEMBL3204361 | 0.79 | GPR52 (0.59) | GPR52S1PR5S1PR4 | |
| SCHEMBL1852511 | 0.79 | GPR52 (0.44) | GPR52S1PR5S1PR4SLC9A1 | |
| SCHEMBL3217946 | 0.78 | GPR52 (0.79) | GPR52KDM1A | |
| SCHEMBL1851157 | 0.78 | GPR52 (0.57) | GPR52SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |