Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941245 | 1.00 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL7956090 | 1.00 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL15947711 | 1.00 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL7723401 | 0.93 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL7723403 | 0.93 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL15941034 | 0.90 | SGMS2 (0.58) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL15941211 | 0.90 | SGMS2 (0.58) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL7761787 | 0.90 | SGMS2 (0.58) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL17389356 | 0.85 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL15947736 | 0.85 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310058-B1 | N-HYDROXYAZEPIN-2-ONES SUBSTITUTED AT 3 POSITION WITH A GROUP CONTAINING A 2-PHENYLOXAZOLE OR 2-PHENYLOXAZOLINE GROUP FOR TREATING TUBERCULOSIS | UNIVERSITY OF NOTRE DAME DU LAC | 2001-10-30 | — | — | US | disclosed |