Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411260 | 0.81 | CYP1A1 (0.45) | MAOBMAOAMAPTAHRCYP1A1 | |
| SCHEMBL24993379 | 0.81 | AHR (0.53) | MAOBMAOAMAPTSMN1; SMN2AHR | |
| SCHEMBL89112 | 0.80 | AHR (0.47) | MAOBMAOAMAPTSMN1; SMN2AHR | |
| SCHEMBL31115580 | 0.80 | FFAR1 (0.45) | MAOBMAOAMAPTAHRCYP1A1 | |
| SCHEMBL7147685 | 0.80 | AHR (0.64) | MAOBMAOAMAPTSMN1; SMN2AHR | |
| SCHEMBL378068 | 0.80 | FFAR1 (0.45) | MAOBMAOAMAPTAHRCYP1A1 | |
| SCHEMBL13095989 | 0.80 | MAPT (0.55) | MAOBMAOAMAPTSMN1; SMN2CHRNB2 | |
| SCHEMBL29607136 | 0.79 | PDK2 (0.45) | MAOBMAOAAHR | |
| SCHEMBL228003 | 0.78 | CYP1A1 (0.64) | MAPTAHRCYP1A1CYP1B1 | |
| SCHEMBL14831492 | 0.78 | MAPT (0.53) | MAOBMAOAMAPTSMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010191-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-1997037985-A1 | NONPEPTIDE ENDOTHELIN ANTAGONISTS WITH INCREASED WATER SOLUBILITY | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | disclosed |