Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496909 | 0.86 | MEN1 (0.59) | MEN1KMT2AGAAALDH1A1HSD17B1 | |
| SCHEMBL14544585 | 0.86 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1HSD17B1 | |
| SCHEMBL11572746 | 0.85 | MEN1 (0.54) | MEN1KMT2AGAAALDH1A1HSD17B1 | |
| SCHEMBL8590961 | 0.85 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1HSD17B1 | |
| SCHEMBL3545178 | 0.85 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1HSD17B1 | |
| SCHEMBL9298896 | 0.85 | SMN1; SMN2 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30668842 | 0.85 | SMN1; SMN2 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11877092 | 0.82 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1HSD17B1 | |
| SCHEMBL10891532 | 0.82 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21676273 | 0.82 | KDM4E (0.53) | MEN1KMT2AGAAALDH1A1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |